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Dental Caries — Overview

The most prevalent infectious disease worldwide

Overview

Dental caries is a multifactorial, biofilm-mediated, sugar-driven, dynamic disease that results in the net mineral loss of dental hard tissues.

It is a continuous process of demineralization and remineralization, with disease occurring when demineralization predominates over time.

Modern understanding emphasizes the ecological plaque hypothesis: caries develops when the balance of the oral microbiome shifts toward acidogenic species due to frequent sugar exposure.